LASS6 monoclonal antibody (M01), clone 5H7
产品名称： LASS6 monoclonal antibody (M01), clone 5H7
英文名称： LASS6 monoclonal antibody (M01), clone 5H7
产品编号： H00253782-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant LASS6.
- Immunogen:
- LASS6 (NP_982288, 62 a.a. ~ 131 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- PCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.44 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Modulation of ceramide synthase activity via dimerization.
Laviad EL, Kelly S, Merrill AH Jr, Futerman AH.J Biol Chem. 2012 Apr 26.
- 2.
- D,l-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via ceramide synthase 5 protein expression in A549 cells.
Yamane M, Miyazawa K, Moriya S, Abe A, Yamane S.Biochimie. 2011 May 7. [Epub ahead of print]
- 3.
- Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells.
Mesicek J, Lee H, Feldman T, Jiang X, Skobeleva A, Berdyshev EV, Haimovitz-Friedman A, Fuks Z, Kolesnick R.Cell Signal. 2010 Apr 18. [Epub ahead of print]
- 4.
- Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer.
Ruckhaberle E, Holtrich U, Engels K, Hanker L, Gatje R, Metzler D, Karn T, Kaufmann M, Rody A.Climacteric. 2009 Jul 31:1-12. [Epub ahead of print]
- Applications
- Western Blot (Cell lysate)
- LASS6 monoclonal antibody (M01), clone 5H7 Western Blot analysis of LASS6 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to LASS6 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged LASS6 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Related Disease