ID4 (Human) Recombinant Protein (Q01)
产品名称: ID4 (Human) Recombinant Protein (Q01)
英文名称: ID4 (Human) Recombinant Protein (Q01)
产品编号: H00003400-Q01
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
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 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Human ID4 partial ORF ( NP_001537, 60 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
 
- Sequence:
 - PALCLQCDMNDCYSRLRRLVPTIPPNKKVSKVEILQHVIDYILDLQLALET
 
- Theoretical MW (kDa):
 - 31.35
 
- Preparation Method:
 - in vitro wheat germ expression system
 
- Purification:
 - Glutathione Sepharose 4 Fast Flow
 
- Storage Buffer:
 - 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
 
- Storage Instruction:
 - Store at -80°C. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - 12.5% SDS-PAGE Stained with Coomassie Blue.

 
- Note:
 - Best use within three months from the date of receipt of this protein.
 
- MSDS:
 
Download
- Application Image
 
- Enzyme-linked Immunoabsorbent Assay
 
- Western Blot (Recombinant protein)
 
- Antibody Production
 
- Protein Array
 
- Entrez GeneID:
 - 3400
 
- GeneBank Accession#:
 - NM_001546
 
- Protein Accession#:
 - NP_001537
 
- Gene Name:
 - ID4
 
- Gene Alias:
 - IDB4,bHLHb27
 
- Gene Description:
 - inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
 
- Omim ID:
 - 600581
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - Transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins (Pagliuca et al., 1995 [PubMed 7665172]).[supplied by OMIM
 
- Other Designations:
 - OTTHUMP00000016081
 
- Gene Pathway
 
